2022 Tiburon Challenger – Singles

Tommy Paul was the defending champion but chose not to defend his title.

Zachary Svajda won the title after defeating Ben Shelton 2–6, 6–2, 6–4 in the final.

Seeds
• # 🇺🇸 Denis Kudla (semifinals, retired)

• # 🇺🇸 Stefan Kozlov (second round)

• # 🇺🇸 Michael Mmoh (second round)

• # 🇺🇸 Ben Shelton (final)

• # 🇫🇷 Enzo Couacaud (quarterfinals)

• # 🇨🇳 Shang Juncheng (first round)

• # 🇺🇸 Ernesto Escobedo (quarterfinals)

• # 🇺🇸 Mitchell Krueger (quarterfinals)