2022 Vilnius Open – Singles

This was the first edition of the tournament.

Mattia Bellucci won the title after defeating Cem İlkel 1–6, 6–3, 7–5 in the final.

Seeds
• # 🇨🇿 Tomáš Macháč (first round)

• # 🇱🇹 Ričardas Berankis (second round)

• # 🇮🇹 Matteo Arnaldi (first round)

• # 🇮🇹 Gianluca Mager (second round)

• # 🇸🇰 Lukáš Klein (quarterfinals)

• # 🇧🇦 Nerman Fatić (second round)

• # 🇫🇷 Laurent Lokoli (quarterfinals)

• # 🇫🇷 Antoine Escoffier (quarterfinals)