2022 Western & Southern Open – Men's singles

Borna Ćorić defeated Stefanos Tsitsipas in the final, 7–6(7–0), 6–2 to win the men's singles tennis title at the 2022 Cincinnati Masters. It was his first Masters 1000 title, and his first title overall since the 2018 Halle Open. Ranked No. 152 in the world and using a protected ranking for entry, Ćorić became the lowest ranked player to win a Masters event since the series' inception in 1990. He defeated five seeded players en route to the title.

Alexander Zverev was the reigning champion, but did not participate due to a long-term ankle injury.

Rafael Nadal and Daniil Medvedev were in contention for the ATP No. 1 ranking. Medvedev retained the top ranking after Nadal lost in the second round to Ćorić.

Seeds
The top eight seeds receive a bye into the second round. • Daniil Medvedev (semifinals)

• 🇪🇸 Rafael Nadal (second round)

• 🇪🇸 Carlos Alcaraz (quarterfinals)

• Stefanos Tsitsipas (final)

• 🇳🇴 Casper Ruud (second round)

•  Andrey Rublev (third round)

• 🇨🇦 Félix Auger-Aliassime (quarterfinals)

• 🇵🇱 Hubert Hurkacz (second round)

• 🇬🇧 Cameron Norrie (semifinals)

• 🇮🇹 Jannik Sinner (third round)

• 🇺🇸 Taylor Fritz (quarterfinals)

• 🇮🇹 Matteo Berrettini (first round)

• 🇦🇷 Diego Schwartzman (third round)

•  Marin Čilić (third round)

• 🇪🇸 Roberto Bautista Agut (third round)

• 🇧🇬 Grigor Dimitrov (first round)

Finals


Seeded players
The following are the seeded players. Seedings are based on ATP rankings as of August 8, 2022. Rank and points before are as of August 15, 2022.

Points for the 2021 tournament were not mandatory and are included in the table below only if they counted towards the player's ranking as of August 15, 2022. Players who are not defending points from the 2021 tournament will instead have their 19th best result replaced by their points from the 2022 tournament.

† This column shows either the player's points from the 2021 tournament or his 19th best result (shown in brackets). Only ranking points counting towards the player's ranking as of August 15, 2022, are reflected in the column.

Withdrawn players
The following players would have been seeded, but withdrew before the tournament began.

Wild cards
• 🇺🇸 Sebastian Korda

• 🇺🇸 Mackenzie McDonald

• 🇺🇸 Ben Shelton

• 🇺🇸 J. J. Wolf

Protected ranking
• Borna Ćorić

•  Stan Wawrinka

Withdrawals
• 🇰🇿 Alexander Bublik → replaced by 🇮🇹 Fabio Fognini

• 🇷🇸 Novak Djokovic → replaced by 🇺🇸 Brandon Nakashima

• 🇫🇷 Gaël Monfils → replaced by 🇦🇺 Nick Kyrgios

• 🇺🇸 Reilly Opelka → replaced by 🇸🇰 Alex Molčan

• 🇩🇪 Oscar Otte → replaced by 🇫🇮 Emil Ruusuvuori

• 🇦🇹 Dominic Thiem → replaced by 🇷🇸 Filip Krajinović

• 🇩🇪 Alexander Zverev → replaced by 🇫🇷 Benjamin Bonzi

Seeds
• # 🇮🇹 Lorenzo Musetti (qualified)

• # 🇬🇧 Andy Murray (moved to main draw)

• # Ilya Ivashka (qualifying competition)

• # 🇪🇸 Pedro Martínez (first round)

• # 🇮🇹 Lorenzo Sonego (qualified)

• # 🇪🇸 Jaume Munar (qualified)

• # 🇺🇸 Marcos Giron (qualified)

• # João Sousa (withdrew)

• # 🇮🇹 Fabio Fognini (qualifying competition, lucky loser)

• # 🇧🇪 David Goffin (qualified)

• # 🇧🇷 Thiago Monteiro (qualifying competition)

• # 🇷🇸 Dušan Lajović (qualifying competition)

• # 🇫🇷 Adrian Mannarino (first round)

• # 🇦🇺 Thanasi Kokkinakis (qualified)

Qualifiers
• # 🇮🇹 Lorenzo Musetti

• # Henri Laaksonen

• # 🇦🇺 Thanasi Kokkinakis

• # 🇧🇪 David Goffin

• # 🇮🇹 Lorenzo Sonego

• # 🇪🇸 Jaume Munar

• # 🇺🇸 Marcos Giron

Lucky loser
• # 🇮🇹 Fabio Fognini