2022 Western & Southern Open – Women's doubles

Lyudmyla Kichenok and Jeļena Ostapenko defeated Nicole Melichar-Martinez and Ellen Perez in the final, 7–6(7–5), 6–3 to win the women's doubles tennis title at the 2022 Cincinnati Open.

Samantha Stosur and Zhang Shuai were the defending champions, but chose not to compete together. Stosur partnered Latisha Chan, but they lost in the first round to Anna Danilina and Beatriz Haddad Maia. Zhang partnered Ena Shibahara, they lost in the second round to Danilina and Haddad Maia.

Coco Gauff, Elise Mertens and Kateřina Siniaková were in contention for the WTA No. 1 doubles ranking. Gauff retained the top ranking despite withdrawing from the tournament, following Siniaková's loss in the second round and Mertens' loss in the semifinals.

Seeds
The top four seeds received a bye into the second round. • # Veronika Kudermetova / 🇧🇪 Elise Mertens (semifinals)

• # 🇨🇿 Barbora Krejčíková / 🇨🇿 Kateřina Siniaková (second round)

• # 🇯🇵 Ena Shibahara / 🇨🇳 Zhang Shuai (second round)

• # 🇺🇸 Coco Gauff / 🇺🇸 Jessica Pegula (withdrew)

• # 🇨🇦 Gabriela Dabrowski / 🇲🇽 Giuliana Olmos (quarterfinals)

• # 🇺🇸 Desirae Krawczyk / Demi Schuurs (semifinals)

• # 🇺🇦 Lyudmyla Kichenok / Jeļena Ostapenko (champions)

• # 🇨🇳 Xu Yifan / 🇨🇳 Yang Zhaoxuan (second round)

Seeded teams
The following are the seeded teams, based on WTA rankings as of August 8, 2022.

Wild cards
• 🇺🇸 Jessie Aney / 🇺🇸 Ingrid Neel

• 🇺🇸 Caty McNally / 🇺🇸 Taylor Townsend

Protected ranking
• Latisha Chan / 🇦🇺 Samantha Stosur

• 🇧🇪 Kirsten Flipkens / 🇪🇸 Sara Sorribes Tormo

Alternates

 * Ekaterina Alexandrova / Aliaksandra Sasnovich
 * 🇫🇷 Caroline Garcia / Petra Martić

Withdrawals

 * 🇺🇸 Coco Gauff / 🇺🇸 Jessica Pegula → replaced by Ekaterina Alexandrova /  Aliaksandra Sasnovich
 * 🇬🇧 Emma Raducanu / 🇰🇿 Elena Rybakina → replaced by 🇫🇷 Caroline Garcia / Petra Martić