2022 Wimbledon Championships – Wheelchair women's singles

Defending champion Diede de Groot defeated Yui Kamiji in the final, 6–4, 6–2 to win the ladies' singles wheelchair tennis title at the 2022 Wimbledon Championships. It was the third step in an eventual Grand Slam for de Groot, and her seventh consecutive major singles title. Kamiji was attempting to complete the career Grand Slam.

Seeds
• # Diede de Groot (champion)

• # 🇯🇵 Yui Kamiji (final)