2022 World Para Swimming Championships – Men's 150 metre individual medley

The men's 150m individual medley events at the 2022 World Para Swimming Championships were held at the Penteada Olympic Swimming Complex in Madeira between 12–18 June.

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11 swimmers from 11 nations took part. The swimmers with the top eight times, regardless of heat, advanced to the final.
 * Heats

The final was held on 13 June 2022.
 * Final