2022 Zamboanga Family's Brand Sardines season

The 2022 Zamboanga Family's Brand Sardines season was the third season of the franchise in the Maharlika Pilipinas Basketball League (MPBL).

After reaching the division semifinals in their previous campaign, Zamboanga opened their 2022 season with an eight-game winning streak. This would be followed by a stretch of three consecutive losses, which would become the only losses of their entire regular season run. The Family's Brand Sardines then finished with a ten-game winning streak to cap off with an 18–3 record and the top seed in the South Division.

After sweeping Muntinlupa and then defeating Bacolod in a three-game series, Zamboanga faced against the Batangas City Embassy Chill for the third consecutive season. Despite losing game 1 at home, Zamboanga would then win the next two games, with a close win in game 3 clinching their spot in the 2022 national finals against the Nueva Ecija Rice Vanguards. Down 0–2, Zamboanga came home to win game 3 of the series, but would ultimately lose game 4, ending their chances at a championship.

The team played all of their home games this season at the Mayor Vitaliano D. Agan Coliseum in Zamboanga City.