2023–24 CAF Confederation Cup knockout stage

The 2023–24 CAF Confederation Cup knockout stage started on 31 March with the quarter-finals and ended on 19 May 2024 with the second leg of the final to decide the champions of the 2023–24 CAF Confederation Cup. A total of eight teams competed in the knockout stage.

Times are local.

Round and draw dates
The schedule was as follows.

Format
Each tie in the knockout phase was played over two legs, with each team playing one leg at home. The team that scored more goals on aggregate over the two legs advanced to the next round. If the aggregate score was level, the away goals rule was applied, i.e. the team that scored more goals away from home over the two legs advanced. If away goals were also equal, then extra time was not played and the winners were decided by a penalty shoot-out (Regulations III. 26 & 27).  The mechanism of the draws for each round was as follows:
 * In the draw for the quarter-finals, the four group winners were seeded, and the four group runners-up were unseeded. The seeded teams were drawn against the unseeded teams, with the seeded teams hosting the second leg. Teams from the same group could not be drawn against each other, while teams from the same association could be drawn against each other.
 * In the draws for semi-finals, there were no seedings, and teams from the same group or the same association could be drawn against each other. As the draws for the quarter-finals and semi-finals were be held together before the quarter-finals were played, the identity of the quarter-final winners was not known at the time of the semi-final draw.

Qualified teams
The knockout stage involved the 8 teams which qualified as winners and runners-up of each of the eight groups in the group stage. 

Bracket
The bracket of the knockout stage was determined as follows:

 The bracket was decided after the draw for the knockout stage, which was held on 12 March 2024, 14:00 CAT (UTC+2) at the CAF headquarters in Cairo, Egypt.



Quarter-finals
The draw for the quarter-finals was held on 12 March 2024.

Summary
The first legs were played on 31 March, and the second legs were played on 7 April 2024. 


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Matches
Zamalek won 3–2 on aggregate.

RS Berkane won 3–2 on aggregate.

USM Alger won 2–1 on aggregate.

Dreams FC won 3–2 on aggregate.

Semi-finals
The draw for the semi-finals was held on 12 March 2024 (after the quarter-finals draw).

Summary
The first legs were played on 21 April, and the second legs were played on 28 April 2024. 


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Matches
RS Berkane won on walkover after USM Alger withdrew.

Zamalek won 3–0 on aggregate.

Final
 The first leg was played on 12 May, and the second leg was played on 19 May 2024.


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''2–2 on aggregate. Zamalek won on away goals.''