2023 Africa Cup of Nations qualification Group E

Group E of the 2023 Africa Cup of Nations qualification tournament was one of the twelve groups that decided the teams which qualified for the 2023 Africa Cup of Nations finals tournament. The group consisted of four teams: Ghana, Madagascar, Angola and Central African Republic.

The teams played against each other in a home-and-away round-robin format between 1 June 2022 and 7 September 2023.

Ghana and Angola, the group winners and runners-up respectively, qualified for the 2023 Africa Cup of Nations.