2023 Antofagasta Challenger – Singles

This was the first edition of the tournament.

Camilo Ugo Carabelli won the title after defeating Tristan Boyer 3–6, 6–1, 7–5 in the final.

Seeds
• # 🇦🇷 Juan Manuel Cerúndolo (second round)

• # Tomás Barrios Vera (first round)

• # Alejandro Tabilo (first round)

• # 🇦🇷 Genaro Alberto Olivieri (first round)

• # 🇧🇴 Hugo Dellien (second round)

• # 🇦🇷 Facundo Bagnis (second round, retired)

• # 🇦🇷 Francisco Comesaña (quarterfinals)

• # 🇮🇹 Luciano Darderi (semifinals)