2023 Australian Open – Wheelchair women's singles

Two-time defending champion Diede de Groot defeated Yui Kamiji in the final, 0–6, 6–2, 6–2 to win the women's singles wheelchair tennis title at the 2023 Australian Open. It was her fifth Australian Open singles title and her 17th major singles title overall.

Seeds
• # Diede de Groot (champion)

• # 🇯🇵 Yui Kamiji (final)

• # Aniek van Koot (quarterfinals)

• # Jiske Griffioen (semifinals)