2023 Challenger di Roseto degli Abruzzi – Singles

Manuel Guinard was the defending champion but chose not to defend his title.

Filip Misolic won the title after defeating Raphaël Collignon 4–6, 7–5, 7–6(8–6) in the final.

Seeds
• # 🇦🇹 Filip Misolic (champion)

• # 🇮🇹 Franco Agamenone (quarterfinals)

• # Jelle Sels (second round)

• # 🇺🇸 Emilio Nava (second round)

• # 🇮🇹 Andrea Pellegrino (quarterfinals)

• # 🇨🇿 Dalibor Svrčina (semifinals)

• # 🇷🇴 Nicholas David Ionel (semifinals)

• # 🇧🇪 Gauthier Onclin (quarterfinals)