2023 Columbus Challenger – Singles

Jordan Thompson was the defending champion but chose not to defend his title.

Denis Kudla won the title after defeating Alexis Galarneau 6–2, 6–1 in the final.

Seeds
• # 🇫🇷 Enzo Couacaud (quarterfinals)

• # 🇺🇸 Denis Kudla (champion)

• # 🇪🇨 Emilio Gómez (first round)

• # 🇨🇦 Vasek Pospisil (quarterfinals)

• # 🇺🇸 Tennys Sandgren (second round)

• # 🇨🇦 Alexis Galarneau (final)

• # 🇦🇺 Adam Walton (second round)

• # 🇺🇸 Zachary Svajda (second round)