2023 Emilia-Romagna Open – Women's singles

Ana Bogdan won the title, defeating Anna Karolína Schmiedlová in the final, 7–5, 6–1. It was a rematch of the previous year's second round, with Bogdan also winning.

Mayar Sherif was the reigning champion, but chose to compete in Guadalajara instead.

Seeds
• # 🇸🇰 Anna Karolína Schmiedlová (final)

• # 🇷🇴 Ana Bogdan (champion)

• # 🇫🇷 Clara Burel (first round)

• # 🇧🇬 Viktoriya Tomova (quarterfinals)

• # 🇷🇴 Jaqueline Cristian (quarterfinals)

• # Kaja Juvan (quarterfinals)

• # 🇭🇺 Anna Bondár (semifinals)

• # 🇪🇸 Aliona Bolsova (second round)

Seeds
• # 🇵🇱 Katarzyna Kawa (qualified)

• # 🇮🇹 Camilla Rosatello (qualifying competition)

• # Eva Vedder (qualified)

• # Antonia Ružić (qualified)

Qualifiers
• # 🇵🇱 Katarzyna Kawa

• # 🇮🇹 Dalila Spiteri

• # Eva Vedder

• # Antonia Ružić