2023 Guanajuato Open – Singles

Kamilla Rakhimova won the title, defeating Raluca Șerban in the final, 6–0, 1–6, 6–2.

Zhu Lin was the defending champion, but chose not to participate.

Seeds
• # 🇨🇳 Wang Xinyu (semifinals)

• # 🇩🇪 Tatjana Maria (second round)

• # 🇦🇷 Nadia Podoroska (quarterfinals)

• # Kamilla Rakhimova (champion)

• # 🇺🇸 Emma Navarro (first round)

• # 🇯🇵 Nao Hibino (first round)

• # 🇸🇪 Rebecca Peterson (withdrew)

• # 🇪🇸 Aliona Bolsova (first round)