2023 Internazionali di Tennis Città di Perugia – Singles

Jaume Munar was the defending champion but lost in the quarterfinals to Alexandre Müller.

Fábián Marozsán won the title after defeating Edoardo Lavagno 6–2, 6–3 in the final.

Seeds
• # 🇦🇷 Pedro Cachin (semifinals)

• # 🇪🇸 Albert Ramos Viñolas (second round)

• # 🇪🇸 Jaume Munar (quarterfinals)

• # 🇦🇹 Dominic Thiem (first round)

• # 🇫🇷 Alexandre Müller (semifinals)

• # 🇮🇹 Matteo Arnaldi (withdrew)

• # 🇭🇺 Fábián Marozsán (champion)

• # 🇦🇷 Facundo Bagnis (first round)