2023 Internazionali di Tennis Città di Todi – Singles

Pedro Cachin was the defending champion but chose not to defend his title.

Luciano Darderi won the title after defeating Clément Tabur 6–4, 6–7(5–7), 6–1 in the final.

Seeds
• # 🇭🇺 Zsombor Piros (second round)

• # 🇦🇷 Camilo Ugo Carabelli (withdrew)

• # 🇦🇷 Mariano Navone (first round)

• # Duje Ajduković (second round)

• # 🇮🇹 Andrea Pellegrino (first round)

• # 🇦🇷 Román Andrés Burruchaga (first round)

• # 🇮🇹 Luciano Darderi (champion)

• # 🇮🇹 Francesco Maestrelli (semifinals)