2023 Internazionali di Tennis d'Abruzzo – Singles

Matteo Arnaldi was the defending champion but chose not to defend his title.

Alejandro Tabilo won the title after defeating Benoît Paire 6–1, 7–5 in the final.

Seeds
• # 🇬🇧 Liam Broady (withdrew)

• # 🇦🇷 Thiago Agustín Tirante (quarterfinals)

• # Alejandro Tabilo (champion)

• # 🇫🇷 Benoît Paire (final)

• # 🇧🇪 Kimmer Coppejans (quarterfinals)

• # 🇧🇬 Dimitar Kuzmanov (second round)

• # 🇷🇴 Nicholas David Ionel (semifinals)

• # 🇺🇸 Nicolas Moreno de Alboran (second round)

• # 🇧🇪 Raphaël Collignon (quarterfinals)