2023 Open Castilla y León – Singles

Hugo Grenier was the defending champion but retired from his first round match against Dominik Palán.

Pablo Llamas Ruiz won the title after defeating Antoine Escoffier 7–6(11–9), 7–6(7–5) in the final.

Seeds
• # 🇭🇺 Márton Fucsovics (quarterfinals)

• # 🇫🇷 Hugo Grenier (first round, retired)

• # 🇺🇸 Nicolas Moreno de Alboran (semifinals)

• # 🇺🇸 Emilio Nava (first round)

• # 🇮🇹 Mattia Bellucci (first round)

• # 🇪🇸 Pablo Llamas Ruiz (champion)

• # 🇫🇷 Antoine Escoffier (final)

• # 🇱🇹 Ričardas Berankis (second round)