2023 Puerto Vallarta Open – Singles

Daniel Altmaier was the defending champion but lost in the quarterfinals to Yuta Shimizu.

Benoît Paire won the title after defeating Shimizu 3–6, 6–0, 6–2 in the final.

Seeds
• # 🇩🇪 Daniel Altmaier (quarterfinals)

• # 🇫🇷 Enzo Couacaud (first round)

• # 🇦🇷 Facundo Mena (first round, retired)

• # 🇦🇷 Juan Pablo Ficovich (first round)

• # 🇫🇷 Benoît Paire (champion)

• # 🇨🇦 Gabriel Diallo (first round)

• # 🇰🇷 Hong Seong-chan (first round)

• # 🇬🇧 Jan Choinski (first round)