2023 Western & Southern Open – Women's singles

Coco Gauff defeated Karolína Muchová in the final, 6–3, 6–4 to win the women's singles tennis title at the 2023 Cincinnati Open. It was her first WTA 1000 title and the first WTA 1000 final appearances for both Gauff and Muchová. Gauff became the youngest champion in Cincinnati history. By reaching the final, Muchová debuted in the top ten of the WTA rankings.

Caroline Garcia was the defending champion, but lost in the second round to Sloane Stephens.

Seeds
The top eight seeds received a bye into the second round. • 🇵🇱 Iga Świątek (semifinals)

• Aryna Sabalenka (semifinals)

• 🇺🇸 Jessica Pegula (third round)

• 🇰🇿 Elena Rybakina (third round, retired)

• 🇹🇳 Ons Jabeur (quarterfinals)

• 🇫🇷 Caroline Garcia (second round)

• 🇺🇸 Coco Gauff (champion)

• Maria Sakkari (third round)

• 🇨🇿 Petra Kvitová (second round)

• 🇨🇿 Markéta Vondroušová (quarterfinals)

• 🇨🇿 Barbora Krejčíková (first round)

• 🇧🇷 Beatriz Haddad Maia (first round)

• Belinda Bencic (first round)

• Daria Kasatkina (third round)

• 🇺🇸 Madison Keys (first round)

• Veronika Kudermetova (first round)

Seeded players
The following are the seeded players. Seedings are based on WTA rankings as of 7 August 2023. Rank and points before are as of 14 August 2023.

The event is not mandatory on the women's side and points from the 2022 tournament are included in the table below only if they counted towards the player's ranking as of 14 August 2023. For other players, the points defending column shows the player's 16th best result.

Points defending will be replaced at the end of the tournament by the highest of (a) the player's points from the 2023 tournament, (b) her 17th best result, or (c) points from her second-highest non-mandatory WTA 1000 event.

† Points from the player's 16th best result (for points defending) or 17th best result (for points earned), in each case as of 14 August 2023. ‡ Points from the player's second-best non-mandatory WTA 1000 event, which are required to be counted in her ranking. § No change in points because points from this tournament did not count as one of the player's 16 best results.

Wild cards
• 🇺🇸 Danielle Collins

• Céline Naef

• 🇺🇸 Peyton Stearns

• 🇺🇸 Venus Williams

•  Caroline Wozniacki

Protected ranking
• 🇺🇸 Jennifer Brady

• Anastasia Pavlyuchenkova

Withdrawals
• 🇪🇸 Paula Badosa → replaced by 🇨🇳 Zhu Lin

• 🇨🇿 Barbora Strýcová → replaced by 🇺🇸 Sloane Stephens

• 🇺🇦 Elina Svitolina → replaced by 🇫🇷 Varvara Gracheva

Seeds
• # 🇮🇹 Elisabetta Cocciaretto (moved to main draw)

• # 🇫🇷 Varvara Gracheva (qualifying competition, lucky loser)

• # 🇺🇦 Lesia Tsurenko (first round)

• # 🇺🇸 Alycia Parks (qualifying competition)

• # 🇮🇹 Jasmine Paolini (qualified)

• # 🇺🇸 Lauren Davis (first round)

• # 🇮🇹 Camila Giorgi (first round, retired)

• # 🇨🇿 Linda Nosková (qualified)

• # 🇺🇸 Emma Navarro (qualified)

• # 🇨🇿 Linda Fruhvirtová (first round)

• # 🇷🇴 Ana Bogdan (first round)

• # 🇫🇷 Alizé Cornet (qualifying competition)

• # 🇰🇿 Yulia Putintseva (qualifying competition)

• # 🇮🇹 Martina Trevisan (qualified)

• # 🇨🇴 Camila Osorio (qualifying competition)

• # 🇮🇹 Lucia Bronzetti (first round)

Qualifiers
• # 🇨🇳 Wang Xiyu

• # 🇪🇸 Cristina Bucșa

• # 🇮🇹 Martina Trevisan

• # Aliaksandra Sasnovich

• # 🇮🇹 Jasmine Paolini

• # 🇺🇸 Ann Li

• # 🇺🇸 Emma Navarro

• # 🇨🇿 Linda Nosková

Lucky loser
• # 🇫🇷 Varvara Gracheva