2024 Advantage Cars Prague Open – Men's singles

Dominic Stricker was the defending champion but chose not to defend his title.

Jiří Veselý won the title after defeating Gauthier Onclin 6–2, 3–6, 7–6(7–3) in the final.

Seeds
• # Leandro Riedi (second round)

• # 🇫🇷 Hugo Grenier (first round)

• # 🇦🇷 Marco Trungelliti (second round, retired)

• # 🇩🇪 Rudolf Molleker (quarterfinals)

• # 🇫🇷 Benjamin Bonzi (second round)

• # 🇺🇸 Martin Damm (first round)

• # 🇨🇿 Dalibor Svrčina (first round)

• # 🇸🇰 Alex Molčan (semifinals, retired)