2024 Brisbane International – Men's singles

Grigor Dimitrov defeated Holger Rune in the final, 7–6(7–5), 6–4 to win the men's singles tennis title at the 2024 Brisbane International. This was Dimitrov's second title in Brisbane (after 2017) and his first ATP Tour title overall since the 2017 ATP Finals.

Kei Nishikori was the reigning champion from 2019, when the men's event was last held, but did not participate this year.

Former world No. 1 and 22-time major champion Rafael Nadal made his return to the ATP Tour after almost a year out due to injury, entering the tournament as a wild card. He lost to Jordan Thompson in the quarterfinals.

Seeds
• # Holger Rune (final)

• #🇧🇬 Grigor Dimitrov (champion)

• #🇺🇸 Ben Shelton (first round)

• #🇫🇷 Ugo Humbert (second round, withdrew)

• #🇺🇸 Sebastian Korda (first round)

• #🇦🇷 Sebastián Báez (first round)

• #🇦🇷 Tomás Martín Etcheverry (first round)

• # Aslan Karatsev (first round, retired)

Seeds
• # 🇨🇿 Tomáš Macháč (qualified)

• # 🇫🇷 Grégoire Barrère (qualifying competition)

• # 🇨🇴 Daniel Elahi Galán (qualifying competition)

• # 🇺🇸 Alex Michelsen (qualified)

• # 🇦🇹 Dominic Thiem (qualified)

• # 🇫🇷 Quentin Halys (first round)

• # 🇺🇸 Aleksandar Kovacevic (qualifying competition)

• # 🇦🇷 Diego Schwartzman (qualifying competition)

• # 🇦🇺 James Duckworth (qualified)

• # 🇦🇷 Francisco Comesaña (first round)

• # 🇺🇸 Maxime Cressy (qualifying competition)

• # 🇮🇹 Giulio Zeppieri (qualifying competition)

Qualifiers
• # 🇨🇿 Tomáš Macháč

• # 🇦🇺 James Duckworth

• # 🇦🇺 Li Tu

• # 🇺🇸 Alex Michelsen

• # 🇦🇹 Dominic Thiem

• # 🇸🇰 Lukáš Klein