2024 Credit One Charleston Open – Singles

Danielle Collins defeated Daria Kasatkina in the final, 6–2, 6–1 to win the women's singles tennis title at the 2024 Charleston Open. It was her second consecutive title, after the Miami Open, extending her winning streak to 13 matches. She became just the fourth woman, after Steffi Graf, Martina Hingis, and Serena Williams, to win back-to-back titles in Miami and Charleston.

Ons Jabeur was the defending champion, but lost to Collins in the second round. Jabeur was the only woman to win a set against Collins during the tournament.

Seeds
All seeds received a bye into the second round. • # 🇺🇸 Jessica Pegula (semifinals)

• # 🇹🇳 Ons Jabeur (second round)

• # Maria Sakkari (semifinals)

• # Daria Kasatkina (final)

• # 🇧🇷 Beatriz Haddad Maia (third round)

• # Ekaterina Alexandrova (second round)

• # 🇺🇦 Elina Svitolina (third round)

• # 🇺🇸 Madison Keys (second round)

• # Veronika Kudermetova (quarterfinals)

• # 🇺🇸 Emma Navarro (third round)

• # 🇧🇪 Elise Mertens (quarterfinals)

• # Victoria Azarenka (quarterfinals)

• # 🇺🇦 Dayana Yastremska (second round)

• # 🇨🇦 Leylah Fernandez (second round)

• # 🇺🇦 Anhelina Kalinina (third round)

• # 🇺🇦 Lesia Tsurenko (second round)

Seeds
• # 🇫🇷 Varvara Gracheva (qualified)

• # 🇯🇵 Mai Hontama (first round)

• # 🇺🇸 Claire Liu (qualified)

• # 🇦🇺 Daria Saville (qualified)

• # 🇺🇸 McCartney Kessler (qualifying competition, lucky loser)

• # 🇺🇸 Katie Volynets (qualified)

• # 🇺🇸 Elizabeth Mandlik (first round)

• # 🇺🇸 Sachia Vickery (qualified)

• # 🇦🇺 Astra Sharma (qualifying competition, lucky loser)

• # 🇨🇿 Linda Fruhvirtová (qualifying competition)

• # 🇬🇧 Heather Watson (qualifying competition)

• # 🇺🇸 Ann Li (qualifying competition)

Qualifiers
• # 🇫🇷 Varvara Gracheva

• # 🇷🇴 Gabriela Lee

• # 🇺🇸 Claire Liu

• # 🇦🇺 Daria Saville

• # 🇺🇸 Sachia Vickery

• # 🇺🇸 Katie Volynets

Lucky losers
• # 🇺🇸 McCartney Kessler

• # 🇦🇺 Astra Sharma