2024 Open Comunidad de Madrid – Singles

Alexander Shevchenko was the defending champion but chose not to defend his title.

Stefano Napolitano won the title after defeating Leandro Riedi 6–3, 6–3 in the final.

Seeds
• # 🇯🇵 Taro Daniel (first round)

• # 🇪🇸 Albert Ramos Viñolas (quarterfinals)

• # 🇦🇷 Camilo Ugo Carabelli (withdrew)

• # 🇨🇳 Shang Juncheng (second round)

• # 🇨🇿 Vít Kopřiva (second round)

• # 🇦🇹 Jurij Rodionov (semifinals)

• # 🇫🇷 Harold Mayot (second round)

• # 🇰🇿 Mikhail Kukushkin (semifinals, retired)