27S pre-rRNA (guanosine2922-2'-O)-methyltransferase

27S pre-rRNA (guanosine2922-2'-O)-methyltransferase (, Spb1p (gene), YCL054W (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:27S pre-rRNA (guanosine2922-2'-O-)-methyltransferase. This enzyme catalyses the following chemical reaction


 * S-adenosyl-L-methionine + guanosine2922 in 27S pre-rRNA $$\rightleftharpoons$$ S-adenosyl-L-homocysteine + 2'-O-methylguanosine2922 in 27S pre-rRNA

Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that catalyses the formation of 2'-O-methylguanosine2922.