2A

2A or II-A may refer to:

Roads

 * Alberta Highway 2A
 * Massachusetts Route 2A

Science

 * 2A self-cleaving peptides
 * Alpha-2A adrenergic receptor
 * IARC group 2A
 * Keratin 2A
 * Transcription factor II A

Other

 * Deutsche Bahn, IATA designator
 * Second Amendment (disambiguation)
 * Second Amendment to the United States Constitution, that protects right to keep and bear arms
 * Stalag II-A
 * Telecom 2A, a satellite
 * the number of the French department Corse-du-Sud
 * a strain of the bacterium Lactobacillus sakei
 * 2A, a school size classification used by the University Interscholastic League in Texas, US