3-Isopropylmalate dehydrogenase

3-Isopropylmalate dehydrogenase  is an enzyme that is a part of the isopropylmalate dehydrogenase family, which catalyzes the chemical reactions:
 * (2R,3S)-3-isopropylmalate + NAD+ $$\rightleftharpoons$$ 4-methyl-2-oxopentanoate + CO2 + NADH
 * (2R,3S)-3-isopropylmalate + NAD+ $$\rightleftharpoons$$ (2S)-2-isopropyl-3-oxosuccinate + H+ + NADH
 * (2S)-2-isopropyl-3-oxosuccinate + H+ $$\rightleftharpoons$$ 4-methyl-2-oxopentanoate + CO2