3-Quinuclidone

3-Quinuclidinone is a bicyclic organic compounds with chemical formula HC(C2H4)2(C(O)CH2)N. Its basicity is indicated by the pKa of the conjugate acid, which is 7.2. In contrast quinuclidine is about 100x more basic.

Synthesis and reactions
Its hydrochloride salt can be synthesized by a Dieckman condensation: It is a precursor to quinuclidine. Organic reduction of 3-quinuclidone gives the compound quinuclidine, structurally related to DABCO, which has one additional bridgehead nitrogen atom.