3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase

The enzyme 3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase catalyzes the chemical reaction


 * (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA $$\rightleftharpoons$$
 * (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA + H2O

Nomenclature
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (24R,25R)-3α,7α,12α,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA-forming]. Other names in common use include 46 kDa hydratase 2, and (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl-CoA hydro-lyase.