4,5-DHP-DMT

1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (4,5-DHP-DMT) is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT$2A$, with a Ki of 17.0 nM, and moderate selectivity over related serotonin receptors. It has lower 5-HT$2$ affinity and efficacy than the related compound AL-37350A, but higher lipophilicity.