42

42 may refer to:
 * 42 (number)
 * The years 42 BC and AD 42

Arts, entertainment, and media

 * 42 (dominoes), a game
 * 42 (film), a 2013 biopic about American baseball player Jackie Robinson
 * 42, a 2021 album by Sech
 * 42, the Answer to the Ultimate Question of Life, the Universe, and Everything, from Douglas Adams' series The Hitchhiker's Guide to the Galaxy. Named after or in honor of this:
 * "42" (Doctor Who), a 2007 television episode
 * "42" (2001), the final episode of the television series Buzz Lightyear of Star Command
 * "42" (song), a 2008 song by Coldplay
 * 42, the 2012 debut album of Cthulhu Rise
 * 42: The Wildly Improbable Ideas of Douglas Adams, 2023 book by Kevin Jon Davies
 * 42 Entertainment, an alternate reality games company founded in 2003
 * "42", a song by Mumford & Sons from Delta, 2018
 * "Forty Two", a song by Karma to Burn from the album Appalachian Incantation, 2010

Other uses

 * 42 (school), a French computer programming school
 * The 42 (Kolkata), a residential skyscraper in India
 * Tower 42 a skyscraper in London, England
 * 42.zip, a zip bomb
 * 42, Jackie Robinson’s jersey number, since retired by all of Major League Baseball
 * 42, the atomic number of Molybdenum
 * 42 Isis, a main-belt asteroid