5-TFM-DMT

5-TFM-DMT (5-(trifluoromethyl)-DMT, 5-CF3-DMT, 5-(trifluoromethyl)-N,N-dimethyltryptamine) is a putative psychedelic tryptamine derivative related to drugs such as 5-MeO-DMT, 5-Fluoro-DMT, and 5-TFMO-DMT. It acts as a partial agonist at the 5-HT2A receptor, with an EC50 of 185.7 nM and an efficacy of 28.7% (vs 5-HT), and a full agonist at 5-HT2C with an EC50 of 89.7 nM and an efficacy of 88.8%, and no significant activity at 5-HT2B.