A16

A16, A 16, A.16 or A-16 may refer to:
 * A16 road, in several countries
 * ATC code A16, Other alimentary tract and metabolism products, a subgroup of the Anatomical Therapeutic Chemical Classification System
 * British NVC community A16 (Callitriche stagnalis community), a British Isles plant community

It may also refer to:
 * A16, a restaurant in the San Francisco Bay Area
 * Subfamily A16, a rhodopsin-like receptors subfamily
 * One of the Encyclopaedia of Chess Openings codes for the English Opening in chess
 * Washington A16, 2000 Protests in Washington, D.C. against the International Monetary Fund and the World Bank on April 16 of 2000 and 2005, both known as "A16"

Technology

 * Apple A16 Bionic, a system on a chip mobile processor designed by Apple

Transportation

 * Aviadesign A-16 Sport Falcon, an American light-sport aircraft
 * Focke-Wulf A.16, a 1926 German three-four passenger light transport monoplane
 * A16 station, an upcoming MTR station on the West Rail line Tuen Mun South extension