A300 (disambiguation)

The Airbus A300 is a wide-body airliner.

A300 or A.300 may also refer to:
 * A300 road, a main road in Great Britain
 * Acorn Archimedes A300, a British home computer
 * Aero A.300, a 1938 Czechoslovakian bomber aircraft
 * Ansaldo A.300, a 1919 Italian general-purpose biplane aircraft
 * Midland Highway (Victoria), a highway in Victoria, Australia bears the designation A300 for most of its route
 * RFA Oakol (A300), a British fleet auxiliary vessel
 * Weishi A300, a version of Chinese 300 mm rocket artillery
 * AMD A300 platform, a system on a chip solution for AMD Ryzen processors