AE2

AE2 may refer to:


 * HMAS AE2, E-class submarine of the Royal Australian Navy
 * Aero Ae 02, a design of Czechoslovakian plane
 * Anion Exchanger 2, transport protein
 * Ape Escape 2
 * A size designation for Constantinian bronze coins
 * Applied Energistics 2, a popular mod for the video game Minecraft
 * Aminoestradiol, a synthetic estrogen