AEN

AEN is may refer to:


 * Acute esophageal necrosis, a rare esophageal disorder
 * A+E Networks, a media organization based in the United States
 * AEN Ayiou Georgiou Vrysoullon-Acheritou, an association football club in the Agios Georgios refugee settlement in Cyprus
 * Alliance for Europe of the Nations, a pan-European political party
 * Alfred E. Neuman, a fictional character in MAD magazine
 * Armenian Environmental Network
 * Armenian Sign Language
 * asynchronous event notification in (for example) the NC-SI electrical interface