APSA

APSA may refer to :


 * Administration of the Patrimony of the Apostolic See, an institution of the Holy See, Vatican City
 * Aerolíneas Peruanas S.A., the former national airline of Peru
 * African Peace and Security Architecture, a peace and security policy framework of the African Union
 * Alto Palermo S.A., an Argentine real estate company
 * American Pediatric Surgical Association, an American professional association
 * American Physician Scientists Association, a professional organization
 * American Political Science Association, a professional association
 * APSA Colombia, an airline based in Bogotá, Colombia
 * Asia Pacific Screen Awards, an international cultural initiative of the UN, based in Australia
 * London All Peoples' Sports Association football club, a non-League football team who play in the Essex Senior Football League