APSC

APSC may refer to:
 * APSC Pariyaram, the Academy of Pharmaceutical Sciences, Pariyaram
 * APS-C, the Advanced Photo System type-C image sensor format
 * The African People's Solidarity Committee, a committee of the African People's Socialist Party
 * Alaska Police Standards Council
 * The Arkansas Public Service Commission
 * The Australian Public Service Commission
 * The Association of Southeast Asian Nations Political-Security Community
 * The Assam Public Service Commission
 * The Army Public School, Chennai, a public school in Chennai, India