Acetoacetyl-CoA hydrolase

The enzyme acetoacetyl-CoA hydrolase (EC 3.1.2.11) catalyzes the reaction


 * acetoacetyl-CoA + H2O $$\rightleftharpoons$$ CoA + acetoacetate

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is acetoacetyl-CoA hydrolase. Other names in common use include acetoacetyl coenzyme A hydrolase, acetoacetyl CoA deacylase, and acetoacetyl coenzyme A deacylase. This enzyme participates in butanoate metabolism.