Acetoacetyl-CoA synthase

Acetoacetyl-CoA synthase (, NphT7) is an enzyme with systematic name acetyl-CoA:malonyl-CoA C-acetyltransferase (decarboxylating). This enzyme catalyses the following chemical reaction


 * acetyl-CoA + malonyl-CoA $$\rightleftharpoons$$ acetoacetyl-CoA + CoA + CO2

The enzyme from the soil bacterium ''Streptomyces sp. CL190'' produces acetoacetyl-CoA.