Acetone hydrazone

Acetone hydrazone (isopropylidenehydrazine) is the product of condensation of acetone and hydrazine, as typical for hydrazone formation. It is an intermediate in the synthesis of 2-diazopropane.


 * Acetone hydrazone to 2-diazopropane.png

Acetone hydrazone can be produced on large scale by reaction of acetone azine with hydrazine, a more convenient reaction than direct reaction of acetone and hydrazine. Likewise, it is susceptible to disproportionation to revert to acetone azine and hydrazine, especially in the presence of water.


 * Acetone azine to acetone hydrazone.png

The chemical is one of the metabolic products of the antihypertensive pharmaceutical hydralazine, and itself also have antihypertensive effects.