Afzal Khan

Afzal Khan may refer to:


 * Afzal Khan (general) (died 1659), Bijapuri general
 * Afzal Khan (actor) (born 1966), Pakistani actor
 * Afzal Khan Shirazi, Mughal administrator and prime minister
 * Mir Afzal Khan, former Pakistani politician
 * Afzal Khan Lala (1926–2015), Pashtun nationalist
 * Afzal Khan (British politician) (born 1958), UK Member of Parliament and former Member of the European Parliament
 * Afzal Ahmed Khan, Indian film director and producer
 * Afzal Rahman Khan (1921–2005), Pakistan Navy admiral and politician
 * Afzal Khan Khattak, Pashtun chief of the Khattak tribe
 * Afzal Kahn (automotive designer) (born 1964), British automotive designer
 * Afzal H. Khan, Bangladesh politician