Agnes Macdonald

Agnes Macdonald may refer to:
 * Agnes Macdonald, 1st Baroness Macdonald of Earnscliffe, second wife of Sir John A. Macdonald
 * Agnes Syme Macdonald, Scottish suffragette
 * Agnes Gertrude VanKoughnet, Canadian socialite and second wife of Hugh John Macdonald
 * Agnes MacDonald, one of the MacDonald sisters, Scottish women notable for their marriages to well-known men