Alpha-bisabolene synthase

α-Bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-α-bisabolene-forming).

This enzyme catalyses the following chemical reaction:


 * (2E,6E)-farnesyl diphosphate $$\rightleftharpoons$$ (E)-α-bisabolene + diphosphate

This synthase requires a divalent cation cofactor (Mg2+ or, to a lesser extent, Mn2+) to neutralize the negative charge of the diphosphate leaving group.