American soccer clubs in international competitions

This is a list of American soccer clubs in international competitions. American clubs have participated in competitive international soccer competitions since 1963, when New York Hungaria entered the 1963 CONCACAF Champions' Cup.

Unlike other major professional sports leagues in the United States, the winners of Major League Soccer are not universally considered to be world champions in their respective sport. Yearly, MLS teams will compete against other soccer clubs abroad in competitions to determine the champions of North America, the Americas, and the world.

Since 1963, American soccer clubs have won three CONCACAF Champions' Cup/Champions League titles, and finished runners-up four times.

Who qualifies for CONCACAF competitions
For the CONCACAF Champions Cup, up to nine American soccer clubs are eligible for entry into the competition. Starting in 2024, all MLS clubs (United States or Canada based) may qualify through MLS or Leagues Cup.

If one (or more) MLS club(s) were to qualify through multiple methods, then the next MLS club(s) with the most overall table points, regardless of conference, would qualify in the remaining slot(s). If the U.S. Open Cup champion has qualified through multiple methods, then the runner-up would fill the slot; should the runner-up have already qualified, then the next best MLS club in the overall table would earn the slot. If the Leagues Cup champion were to win the MLS Cup, then the MLS Cup runner-up would qualify to the round of 16; should the Leagues Cup slot(s) have already qualified, then MLS would be awarded with one additional slot to be given to the next best non-qualified team in the overall table.

In past competitions, such as the North American SuperLiga (held from 2007 to 2010), the best teams based on regular season record to not qualify for the Champions League participated.

Full international record
Competitive tournaments only.

CONCACAF Champions' Cup / Champions League
The competition was named CONCACAF Champions' Cup until 2008 and CONCACAF Champions League until 2024, when it was renamed back to CONCACAF Champions Cup.

Appearances in CONCACAF competitions
As of March 11, 2021.