Aminomethyl propanol

Aminomethyl propanol (AMP) is an organic compound with the formula H2NC(CH3)2CH2OH. It is colorless liquid that is classified as an alkanolamine. It is a useful buffer and a precursor to numerous other organic compounds.

Aminomethyl propanol is typically sold as a solution of the material in water, for which different concentrations are available.

Synthesis
Aminomethyl propanol can be produced by the hydrogenation of 2-aminoisobutyric acid or its esters.

Properties
Aminomethyl propanol is soluble in water and about the same density as water.

Uses
Aminomethyl propanol is used for the preparation of buffer solutions. It is a component of the drugs ambuphylline and pamabrom. It is also used in cosmetics.

It is a precursor to oxazolines via its reaction with acyl chlorides. Via sulfation of the alcohol, the compound is also a precursor to 2,2-dimethylaziridine.

Aminomethyl propanol is used as an intermediate the synthesis of fepradinol, isobucaine, and radafaxine.