Andy O'Brien

Andy or Andrew O'Brien may refer to:


 * Andy O'Brien (footballer) (born 1979), Irish footballer
 * Andy O'Brien (hurler) (born 1988), Irish hurler
 * Andy O'Brien (journalist) (1910–1987), Canadian sports journalist
 * Andy O'Brien (politician) (1915–2006), Irish Fine Gael senator
 * Andrew O'Brien (politician) (fl. 1990s-2010s), US Department of State official
 * Andrew O'Brien (rugby) (1897–1969), New Zealand rugby footballer

Fictional

 * Andy O'Brien (EastEnders), a character in EastEnders