Apalachicola

Apalachicola may refer to:


 * Apalachicola band, an association of Native American towns along the Apalachicola River in Florida in the early 19th century
 * Apalachicola Province, an association of Native American towns on the Chattahoochee River in Alabama and Georgia that became the Lower Towns of the Muscogee Confederacy
 * Apalachicola (tribal town), a Native American town that was the namesake of the Apalachicola Province

Places

 * Apalachicola, Florida
 * Apalachicola River
 * Apalachicola Bay
 * Apalachicola National Forest
 * Apalachicola Regional Airport
 * Port of Apalachicola

Railroad

 * Apalachicola and Alabama Railroad
 * Apalachicola Northern Railroad

Ships

 * Apalachicola, a tugboat in the United States Navy.