Arsenate reductase (glutaredoxin)

Arsenate reductase (glutaredoxin) is an enzyme that catalyzes the chemical reaction


 * arsenate + glutaredoxin $$\rightleftharpoons$$ arsenite + glutaredoxin disulfide + H2O

Thus, the two substrates of this enzyme are arsenate and glutaredoxin, whereas its 3 products are arsenite, glutaredoxin disulfide, and water.

This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with disulfide as acceptor. The systematic name of this enzyme class is glutaredoxin:arsenate oxidoreductase.

Structural studies
As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , and.